Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells
Fig 4
Number of CCR6 mRNA and protein positive cells in lamina propria.
Number of CCR6 immunohistochemically (IHC) and in situ hybridization (ISH) positive cells in colonic biopsies from healthy controls (N), active (UCa) or inactive (UCi) ulcerative colitis, and active (CDa) or inactive (CDi) Crohn’s disease. Five subjects in each group for IHC, and three for ISH. CCR6 positive cells were counted in ten 15,000μm2 areas of lamina propria for each section. * p< 0.05, ** p<0.01, # p<0.05 versus corresponding inactive disease group. Mean ± SD shown.