Characterization of a New Vaccinia virus Isolate Reveals the C23L Gene as a Putative Genetic Marker for Autochthonous Group 1 Brazilian Vaccinia virus
Figure 5
Nucleotide sequence alignment of C23L coding DNA sequences.
Sequences were retrieved from GenBank and aligned using ClustalW method as implemented in the MEGA 4.0 program. The DMTV-2005 isolate showed a 10-nt deletion that leads to an early stop-codon and most likely results in non-functional protein production. The same deletion was observed in the Brazilian VACV Group 1 strains, including DMTV-2005. Nevertheless, the Brazilian Group 2 strains had no deletion in C23L. The deletion site is highlighted with a red box.