Summary
A systematic search for restriction fragment length polymorphisms (RFLPs) on the human Y chromosome was performed. DNA samples from 16–34 individuals were screened with five restriction enzymes and 12 Y-chromosomal probes, 3 of which detect lowly repetitive sequences and 9 of which are apparently single copy in genomic DNA. None of the single-copy probes revealed any variation. The repetitive sequence probe p21A1 (DYZ?) revealed a TaqI RFLP with q = 0.05. The frequency of fixed point mutations in Y-chromosomal DNA outside the pseudoautosomal region is probably less than 1 in 18000 bp.
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Jakubiczka, S., Arnemann, J., Cooke, H.J. et al. A search for restriction fragment length polymorphism on the human Y chromosome. Hum Genet 84, 86–88 (1989). https://doi.org/10.1007/BF00210680
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DOI: https://doi.org/10.1007/BF00210680