Structural basis of human ORP1-Rab7 interaction for the late-endosome and lysosome targeting
Fig 2
Overall structure of human ORP1 ANK and Rab7 complex.
(A) Cylindrical representation of the ORP1-Rab7 complex. The bound GTP and Mg2+ ion are shown in spheres. The disordered C-terminus of Rab7 is indicated with a dotted line. Top view of the structure is shown in the right panel. (B) 2.1 Å 2F0-Fc electron density maps with the final model superimposed. The Rab7 structure is shown in green and ORP1 ANK in blue. (C) Overall structure of human ORP1 ANK domain.