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Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients

Fig 2

Mean (± SEM) genome-wide Euclidean distance between promoter-specific DNA methylation of obese patients and controls before and at 6 month after Roux-en Y gastric bypass surgery.

The left panel illustrates the mean Euclidean distance at genome-wide scale, whereas the right panel shows the mean Euclidean distance at single-gene promoter scale. A two-tailed p-value <0.05 was considered significant.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0115186.g002