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Identifying Cancer Specific Functionally Relevant miRNAs from Gene Expression and miRNA-to-Gene Networks Using Regularized Regression

Figure 2

Robustness to network noise.

(A) Sensitivity and (B) precision of the method in predicting the gene-expression-driving miRNAs when we varying the proportions of incorrect edges and missing edges in the miRNA-Gene interactions network (delete edges/insert new edges). All miRNA were also predicted to have the correct direction of influence (suppressor vs oncogene effect).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0073168.g002