Regulation of Inflammatory Chemokine Receptors on Blood T Cells Associated to the Circulating Versus Liver Chemokines in Dengue Fever
Figure 4
Phenotype of CCR5- or CXCR3 among CD4 and CD8 T cells from DENV-patients.
Representative histogram plots comparing (A) the frequency of CD38+ or CD107a+ among CD4+CCR5+ T cells and (B) the frequency of CD38+ or CD107a+ among CD8+CCR5+ T cells between one healthy control (gray line) and one DENV-patient (black line). Vertical bars indicate the positive values based an appropriate matched isotype control antibodies. Percentage of CCR5+CD4+ (C) or CCR5+CD8+ T cells (D) expressing among CD38+ or CD107a+; percentage of CXCR3+CD4+ (E) or CXCR3+CD8+-T cells expressing among CD38+ or CD107a+. Horizontal bars indicate the mean values, standard deviation for each population. The Mann–Whitney U-test was used to analyze differences between control and patient groups. Statistically significant P values for differences between patients and controls are shown above the figures.