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A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium

Figure 3

Stratified analysis of 4 replicated SNPs located near alcohol metabolism genes.

Estimates for rs1229984 (ADH1B), rs1573496 (ADH7), rs1042758 (ADH1C) and rs4767364 (ALDH2) were derived from a log-additive genetic model. ORs were adjusted by age, sex, study and were derived from fixed effects models. “Generic” controls were not included in this analysis.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1001333.g003