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Pharmaceuticals

A new grammar for drug discovery

To realize the potential of the genome for identifying candidate drugs we must move beyond individual genes and proteins. The signalling pathways in cells provide the right level for such analyses.

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Figure 1: Drug-discovery timeline.
Figure 2: Four signalling pathways linked to disease.

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Fishman, M., Porter, J. A new grammar for drug discovery. Nature 437, 491–493 (2005). https://doi.org/10.1038/437491a

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