Abstract
A method based on the sorption of99mTc in MEK on an acid alumina column has been investigated. A number of parameters as column dimension, amount of alumina, MEK volumes, etc. is found to affect the extent of adsorption and the final purity of99mTc solution. These parameters have been standardized and a method for rapid recovery of MEK-extracted99mTc has been developed. The final characteristics of the99mTc is found to conform to pharmacopoeia specification.
Similar content being viewed by others
References
J. B. Gerlit, Proc. Int. Conf. Peaceful Uses of Atomic Energy, Geneva, UNO, New York, 7 (1956) 1945.
P. Richards, Report BNL-9601/1 (1965).
P. Richards, V. D. Tucker, S. C. Srivastava,Int. J. Appl. Radiation Isotopes, 33 (1982) 739.
R. S. Mani, D. V. S. Narasimhan, Radiopharmaceuticals and labelled compounds — Proc. Symp. Copenhangen, IAEA, Vienna, 1 (1973) 135–148.
K. Svoboda,Nucleon, 3 (1988) 16.
K. Svoboda, Conference Transactions No. IAEA-SR-131/21, IAEA, Vienna (1986).
T. Braun, H. Imura, N. Suzuki,J. Radioanal. Nucl. Chem. Lett., 119 (1987) 315.
S. N. Muddukrishna, D. V. S. Narasimhan, C. N. Desai,J. Radioanal. Nucl. Chem. Lett., (in press).
S. Tachimori, H. Amano, H. Nakamura,J. Nucl. Sci. Technol., 8 (1971) 357.
S. N. Muddukrishna, D. V. S. Narasimhan, C. N. Desai,J. Radioanal. Nucl. Chem., Articles, 140 (1990) 153.
U. S. Pharmacopoeia, XIX (1975).
BARC solvent extraction99mTc-Generator Product Brochure.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Muddukrishna, S.N., Narasimhan, D.V.S., Iyer, S.P. et al. A rapid method for recovery of radiochemically pure99mTc from MEK extracts. Journal of Radioanalytical and Nuclear Chemistry Letters 146, 235–244 (1990). https://doi.org/10.1007/BF02164191
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02164191