Abstract
A convenient synthetic pathway for 14C labeling of fentanyl [N-(1-phenethyl-4-piperidinyl)- propionanilide], a widely used narcotic analgesic agent, with good radiochemical yield was developed.
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Higashikawa, Y. and Suzuki, S., Forens. Toxicol., 2008, vol. 26, no. 1, pp. 1–5.
Helsley, G.C., Lunsford, C.D., Welstead, W.J., Jr., et al., J. Med. Chem., 1969, vol. 12, no. 4, pp. 583–586.
Van Bever, W.F.M., Niemegeers, C.J.E., and Janssen, P.A.J., J. Med. Chem., 1974, vol. 17, pp. 1047–1050.
Vuckovic, S.M., Ivanovic, M.D., Prostran, M.S., et al., Jpn. J. Pharmacol., 1998, vol. 78, no. 4, pp. 523–527.
Ivanovic, M.D., Vuckovic, S., Ristovic, Z., et al., Iugoslav. Physiol. Pharmacol. Acta, 1995, vol. 31, pp. 195–199.
Perry, C.W., Burger, W., and Delaney, C.M., J. Label. Compd. Radiopharm., 2005, vol. 16, no. 4, pp. 645–649.
Corrie, J.E.T. and Munasinghe, V.R.N., J. Label. Compd. Radiopharm., 2005, vol. 48, pp. 231–233.
Morita, J.I., Nakatsuji, H., Misaki, T., and Tanabe, Y., Green Chem., 2005, vol. 7, pp. 711–715.
Bagley, J.R. and Wilhelm, J.A., J. Label. Compd. Radiopharm., 1992, vol. 31, no. 11, pp. 945–950.
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Published in Russian in Radiokhimiya, 2018, Vol. 60, No. 1, pp. 41–43.
The text was submitted by the authors in English.