Abstract
Historically, cancer treatment has emphasized measures for the “cure” regardless of the long-term consequences. Advances in cancer detection and treatment have resulted in improved outcomes bringing to the fore various quality of life considerations including future fertility. For many young cancer patients, fertility preservation is now an integral component of clinical decision-making and treatment design. Optimal fertility-sparing options for young patients with gynecologic cancer are influenced by patient age, primary cancer, treatment regimens, and patient preferences. Possible approaches include embryo or oocyte cryopreservation, ovarian transposition, conservative surgery, and conservative medical treatment to delay radical surgery. These may be used alone or in combination to maximize fertility preservation. Awareness of the various fertility-sparing options, eligibility criteria, and the central role of magnetic resonance imaging in the proper selection of patients will enable radiologists to produce complete clinically relevant imaging reports and serve as effective consultants to referring clinicians. Knowledge of the potential imaging pitfalls is essential to avoid misinterpretation and guide appropriate management.
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Change history
11 November 2017
The original version of this article unfortunately contained mistakes. The figures 7D, 7E and 7F were missing in the article and arrows were missing in the figures 6C, 8B and 11C. The year of publication and volume number for references 19, 79 and 87 have been updated. Also, the Table 2 layout has been improved for better readability. The Publisher apologizes for the mistakes and the inconvenience caused.
Abbreviations
- ADC:
-
Apparent diffusion coefficient
- D&C:
-
Dilatation and curettage
- DCE-MRI:
-
Dynamic contrast-enhanced MRI
- DWI:
-
Diffusion-weighted imaging
- ESMO:
-
European Society for Medical Oncology
- ESUR:
-
European Society of Urogenital Radiology
- FDG:
-
Fluorodeoxyglucose
- FIGO:
-
International Federation of Gynecology and Obstetrics
- FST1WI:
-
Fat-saturated T1WI
- JZ:
-
Junctional zone
- LVSI:
-
Lymphovascular space invasion
- MRI:
-
Magnetic resonance imaging
- NCCN:
-
National Comprehensive Cancer Network
- OHSS:
-
Ovarian hyperstimulation syndrome
- PET/CT:
-
Positron emission tomography–computed tomography
- PET/MRI:
-
Positron emission tomography–magnetic resonance imaging
- USO:
-
Unilateral salpingo-oophorectomy
- ROI:
-
Region of interest
- SEE:
-
Subendometrial enhancement
- SI:
-
Signal intensity
- T1WI:
-
T1-Weighted imaging
- T2WI:
-
T2-Weighted imaging
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This study was funded in part through the NIH/NCI Cancer Center Support Grant P30 CA008748.
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The original version of this article is revised: “The figures 7D, 7E and 7F were missing in the article and arrows were missing in the figures 6C, 8B and 11C. The year of publication and volume number for references 19, 79 and 87 have been updated. The above mistakes are corrected through erratum. Also, the Table 2 layout has been improved for better readability”. The Publisher apologizes for the mistakes and the inconvenience caused.
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An erratum to this article is available at https://doi.org/10.1007/s00261-017-1205-5.
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McEvoy, S.H., Nougaret, S., Abu-Rustum, N.R. et al. Fertility-sparing for young patients with gynecologic cancer: How MRI can guide patient selection prior to conservative management. Abdom Radiol 42, 2488–2512 (2017). https://doi.org/10.1007/s00261-017-1179-3
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DOI: https://doi.org/10.1007/s00261-017-1179-3