A NEW AMINOGLYCOSIDE ANTIBIOTIC COMPLEX-THE SELDOMYCINS II. ISOLATION, PHYSICOCHEMICAL AND CHROMATOGRAPHIC PROPERTIES

SEUI SATO; SEIGO TAKASAWA; TOMOYASU SATO; MITSUYOSHI YAMAMOTO; RYO OKACHI; ISAO KAWAMOTO; TAKAO IIDA; ATSUKO MORIKAWA; TAKASHI NARA

doi:10.7164/antibiotics.30.25

A NEW AMINOGLYCOSIDE ANTIBIOTIC COMPLEX-THE SELDOMYCINS

II. ISOLATION, PHYSICOCHEMICAL AND CHROMATOGRAPHIC PROPERTIES

SEUI SATO, SEIGO TAKASAWA, TOMOYASU SATO, MITSUYOSHI YAMAMOTO, RYO OKACHI, ISAO KAWAMOTO, TAKAO IIDA, ATSUKO MORIKAWA, TAKASHI NARA

Author information

SEUI SATO
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.
SEIGO TAKASAWA
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.
TOMOYASU SATO
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.
MITSUYOSHI YAMAMOTO
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.
RYO OKACHI
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.
ISAO KAWAMOTO
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.
TAKAO IIDA
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.
ATSUKO MORIKAWA
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.
TAKASHI NARA
Tokyo Research Laboratory, Kyowa Hakko Kogyo Co., Ltd.

JOURNAL FREE ACCESS

1977 Volume 30 Issue 1 Pages 25-30

DOI https://doi.org/10.7164/antibiotics.30.25

Details

Abstract

An antibiotic complex consisting of four components, seldomycin factors 1, 2, 3 and 5 was isolated from the fermentation broth ofStreptomyces hofunensis sp. nov. by use of a cationic exchange resin. After silica gel column chromatography, the purified components were characterized as new aminoglycoside antibiotics by their physicochemical, chromatographic and antimicrobial properties.

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