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An experimental study of MRI–pathology comparison method for soft tissue tumors

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Chinese Journal of Academic Radiology Aims and scope Submit manuscript

Abstract

Purpose

To explore an accurate radiologic–pathologic control method in soft tissue tumor.

Materials and methods

First, we performed a preliminary experimental study of the radiologic–pathologic control method in soft tissue mass simulation model. Targeted localization markers were performed during MRI, surgery, and pathology, to ensure accurate correspondence between MRI slices and pathological sections. And the MRI image after printing was matched with the pathological material surface to obtain the pathological material corresponding to the region of interest (ROI). Second, we performed the same method on soft tissue tumor clinical research population. The long and short diameters of the tumor MRI slices and pathological sections were measured. A paired t test was used to assess differences between them.

Result

A paired t test showed that there were no signifacant differences of the length and diameter of the simulation tumor measured between MRI slices and pathological sections in soft tissue tumor simulation model and clinical research population (p > 0.05).

Conclusion

The “Body position line-MRI slice-Pathological section Five-step Control Method” created by this study could carry out a more accurate radiologic–pathologic comparison study in soft tissue tumors.

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Acknowledgements

This research was supported in part by grants from the National Natural Science Foundation of China (#81771804).

Author information

Author notes

  1. Xiangwen Li, Tang Li and Yu Zhang contributed equally to this work.

Authors and Affiliations

  1. Department of Radiology, The Second Hospital, Dalian Medical University, Dalian, China

    Xiangwen Li, Tang Li, Yu Zhang, Yue Dai, Yawei Xi, Yuan Yuan, Dewei Zeng, Yifeng Zhu, Xiaoyu Zhao, Kai Zhang & Shaowu Wang

  2. Department of Pathology, The Second Hospital, Dalian Medical University, Dalian, China

    Juan Tao

  3. Yingkou Jucheng Development Co., Ltd. of Teaching, Liaoning, China

    Xinze Li

Authors
  1. Xiangwen Li
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  2. Tang Li
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  3. Yu Zhang
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  4. Yue Dai
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  5. Yawei Xi
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  10. Juan Tao
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  11. Kai Zhang
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  12. Xinze Li
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  13. Shaowu Wang
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Correspondence to Shaowu Wang.

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Li, X., Li, T., Zhang, Y. et al. An experimental study of MRI–pathology comparison method for soft tissue tumors. Chin J Acad Radiol 4, 125–132 (2021). https://doi.org/10.1007/s42058-021-00067-1

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  • DOI: https://doi.org/10.1007/s42058-021-00067-1

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