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Assembly of the Murine Leukemia Virus Is Directed towards Sites of Cell–Cell Contact

Figure 9

Monomeric Gag is recruited to cell–cell contact.

(A,B) HEK293 cells transfected with full-length MLV provirus lacking capsid domain (MLVΔCA-GFP, green) were cocultured with XC target cells expressing mCAT1-mCherry (red). MLVΔCA-GFP is recruited to sites of cell–cell contact with accumulation of receptor mCAT1-mCherry. Size bars correspond to 17 µm.

Figure 9

doi: https://doi.org/10.1371/journal.pbio.1000163.g009