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Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans

Fig 8

Immune response landscape of vaccine-matched responses and participant clustering based on vaccine-matched immune responses.

A) Heatmap showing the vaccine-matched CD8+ T-cell polyfunctionality, anti-V1V2 IgG3 antibody binding, CD4+ T-cell polyfunctionality, anti-gp120 IgG3 antibody binding, anti-V1V2 IgG antibody binding, and anti-gp120 IgG antibody binding measurements used to organize participants into the six row clusters. B) The distribution of participants in each trial (column) in each cluster is represented by the row height. Box size is proportional to the number of participants.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0226803.g008