Encapsulated Brucella ovis Lacking a Putative ATP-Binding Cassette Transporter (ΔabcBA) Protects against Wild Type Brucella ovis in Rams
Fig 8
Microscopic changes in the reproductive system of non immunized rams experimentally challenged with Brucella ovis, at 8 weeks post challenge.
Severe neutrophilic epididymitis associated to cystic epithelium degeneration (black arrow), with positive immunestaining for B. ovis (inset, 100X) in the tail of the epididymis from a non immunized ram (A). Tail of the epididymis from a ram immunized with encapsulated B. ovis ΔabcBA and challenged with wild type B. ovis with no histological changes (B). Moderate lympho-histiocytic and neutrophilic inflammatory infiltrate in the ampullae of a non immunized ram (C). Absence of histological changes in the ampullae of a ram immunized with encapsulated B. ovis ΔabcBA and challenged with wild type B. ovis (D), H. E. Bar = 50 μm.