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Experimental Induction of Pulmonary Fibrosis in Horses with the Gammaherpesvirus Equine Herpesvirus 5

Figure 8

Morphometry for interstitial lung collagen (horse C1, E1 shown).

Picrosirius red stained control horse (A) and EHV 5 infected (B); brightfield microscopy. Representative regions analyzed control horse lung (C, shown in ‘a’ above) and EHV 5 infected lung (D, E, shown in ‘b’ above); polarized light microscopy. EHV 5 infected horses had a significant increase in percent collagen within the alveolar parenchyma (F). Magnification: A, B - 2x; C-E - 20x.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0077754.g008