In Vivo Functional Requirement of the Mouse Ifitm1 Gene for Germ Cell Development, Interferon Mediated Immune Response and Somitogenesis
Figure 8
Reporter gene expression in thymus from adult Ifitm1tm1IEG/wt and wildtype mice.
(A and B) Whole organ X-Gal staining of the thymus of heterozygous knockout animals exhibited lacZ expression whereas thymus of wildtype littermate mice did not stain for X-Gal. (C and D) Histological sections of stained thymus revealed cells of the medulla expressing the lacZ reporter gene in Ifitm1tm1IEG/wt mice (C) but not in thymus from wildtype littermate mice (D). Scale bars indicate 100 µm.