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Immune Response of Calves Vaccinated with Brucella abortus S19 or RB51 and Revaccinated with RB51

Fig 7

Subsets of memory (CD45RO+) lymphocytes in peripheral blood mononuclear cells of S19 and RB51 prime vaccinated, and RB51 revaccinated cattle upon in vitro stimulation with ɣ-irradiated B. abortus 2308.

Tendency (median) (a) and box plot (median, first and third quartiles) (b) charts of the results. Whiskers show the lower and upper 1.5 interquartile range. Vaccinations were indicated by arrows. Data of CD45RO+ lymphocytes are shown for CD4+, CD8+ and CD21+ cells. Significant differences (P < 0.05) between vaccination regimens (in same day) are indicated by uppercase letters (Mann-Whitney-test), and lowercase letters indicate statistical difference between days in same group (Skillings Mack test followed by Wilcoxon signed rank test).

Fig 7

doi: https://doi.org/10.1371/journal.pone.0136696.g007