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Ischemic Preconditioning Increases Endothelial Progenitor Cell Number to Attenuate Partial Nephrectomy-Induced Ischemia/Reperfusion Injury

Figure 7

Cell proliferation in three groups at 24h after reperfusion as shown by expression of PCNA in the renal medulla.

(Magnification: ×1000). In Sham tissues (A), there was no or only slight minimal proliferation. PN (B) caused higher proliferation in the renal medulla. IPC (C) caused significantly stronger staining for PCNA. The number of PCNA-positive cells was increased in the PN group when compared to the Sham group, and the IPC group showed a greater increase in PCNA-positive cells when compared to the PN group. Data are shown as mean ± SEM (D). *Significant difference vs. Sham group (P<0.05); #significant difference vs. PN group (P<0.05).

Figure 7

doi: https://doi.org/10.1371/journal.pone.0055389.g007