Cell-to-Cell Transmission Can Overcome Multiple Donor and Target Cell Barriers Imposed on Cell-Free HIV
Figure 7
The relative contribution of cell-free to co-culture mediated transmission is affected by the donor cell type.
Different donor cells (HEK293, HeLa, Jurkat) were co-cultured with HeLa cells expressing CD4/CXCR4, MT4 cells and Jurkat cells. The efficiency of virus transmission in the cell-free mode and in the co-culture-dependent mode was compared as described in Figure 1A. Data for HEK293 donor cells are as Figure 5B. Error bars represent the standard error of the mean from 2 experiments.