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ATRX proximal protein associations boast roles beyond histone deposition

Fig 7

ATRX proteome overview and proposed model.

A: Protein associations with ATRX, FAM207A, and CCDC71. Pale grey circles denote previously reported associations, while dark red circles represent newly identified proximal associations. Blue circles represent previously reported associations also identified by our BioID. Image was built using ProHits Viz [104] and the BioGrid database [52], and manually organized. B: Model proposing new biological roles for ATRX (other than histone deposition), mediated through proximal associations with FAM207A, CCDC71, and SLF2.

Fig 7

doi: https://doi.org/10.1371/journal.pgen.1009909.g007