Alzheimer’s risk factor FERMT2 promotes the progression of colorectal carcinoma via Wnt/β-catenin signaling pathway and contributes to the negative correlation between Alzheimer and cancer
Fig 6
Knockdown of FERMT2 inhibited the migration, invasion and EMT in SW1116 or SW1463 cells.
(A-D) The migration ability of SW1116 or SW1463 cells after FERMT2 knockdown were detected by wound healing assay (A, B) and transwell assay (C, D). Scale bars: 100 μm. (E-H) The expression of E-cadherin, N-cadherin and Vimentin in SW1116 (E-F) or SW1463 (G, H) cells after FERMT2 knockdown were measured by western blot assay. All the tests were repeated at least three times. *P < 0.05, **P < 0.01 vs shNC.