Perturbation of BRMS1 interactome reveals pathways that impact metastasis
Fig 6
SIN3/HDAC members have altered impact on breast cancer outcomes.
(A) Breast Cancer (BRCA) data from TCGA was mined utilizing UALCAN to determine differences in expression of normal compared to tumor tissue. ** indicates a p-value < 0.01. (B-C). BRCA data was mined in which SIN3/HDAC members were separated by median expression into those greater than the median (B) or those less than the median (C). BRMS1 expression was then examined within these patients for overall survival, with High BRMS1 (indicated by Red) and Low BRMS1 (indicated by black) were accounted for. This was completed in KM Plotter.