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Peptides from the Variable Region of Specific Antibodies Are Shared among Lung Cancer Patients

Figure 6

Background determination in NELSON 1 and NELSON 2 datasets.

Twelve times a permutation (Background) was performed on the NELSON 1 and NELSON 2 dataset. The sensitivity and specificity of the antibody peptide model are shown in red. Background assessment: A) Twelve permutation runs are shown with the corresponding sensitivity and specificity of the NELSON 1 dataset (blue). The same 12 peptides found in the background evaluation of NELSON 1 were tested in NELSON 2. B) The 12 runs are shown with the corresponding sensitivity and specificity of NELSON 2 dataset (blue). Note, as some results of the background analysis occurred more than once, a random number between -1 and 1 were added to each sensitivity and specificity number to make sure each analysis (blue dot) can be seen in the figure.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0096029.g006