Predicting Survival within the Lung Cancer Histopathological Hierarchy Using a Multi-Scale Genomic Model of Development
Figure 6
Independent Validation with Separate Human Lung AD Dataset from Beer et al. [ 21]
(A) Survival analyses of 86 human lung ADs by K-M plot with patients separated into two groups by the mouse PC1 median point ( p = 0.0216).
(B) The profiles of the 91 genes (26 cancer up-regulated [green circles] and 65 cancer down-regulated [magenta circles]) among 2,653 mouse lung developmental gene profiles.