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Large-Scale Population Study of Human Cell Lines Indicates that Dosage Compensation Is Virtually Complete

Figure 6

Genes Expressed More Highly in Females Are Distributed Non-Randomly on the X Chromosome

For each gene, the median expression value for males was subtracted from the median expression value for females to give a median difference. Illustrated is the median difference for each gene based on averaging the values for the four populations, plotted according to location on the X chromosome. A median difference of 1 represents a 2-fold difference in expression. Different symbols represent different evolutionary strata. Genes expressed significantly more highly in females are coloured red, and the single gene expressed significantly more highly in males (CD99) is coloured blue.

Figure 6

doi: https://doi.org/10.1371/journal.pgen.0040009.g006