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Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in Diet-Induced Obese Mice Is Associated with Gut Microbial Changes and Reduction in Obesity

Figure 5

High-fat diet and probiotic effect on plasma cholesterol, leptin and insulin.

Effects of probiotic treatment on (A) plasma cholesterol, (B) leptin and (C) insulin in diet-induced obese mice. Results are expressed as the means ± SE. Significant differences between HFD-placebo versus ND are indicated as p<0.05, ††p<0.01. Significant differences between probiotic versus HFD are indicated as *p<0.05.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0059470.g005