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Myosin Light-Chain Kinase Is Necessary for Membrane Homeostasis in Cochlear Inner Hair Cells

Figure 5

Transmission electron microscopy analyses of IHC microstructure.

IHCs from 4-month-old CTR (A–D) and MLCKIKO (E–H) mice were subjected to ultrastructural analysis. “Bubbles” (indicated by asterisks) are located at the top of the cuticular plate in the mutant IHCs (I). The structures of the membranes of the IHC lateral wall (E), cuticular plate (F), mitochondria (G) and stereocilium (H) in IHCs are similar in mice of both genotypes. Scale bars: 2 µm (A, B, E, F and I) or 500 nm (C, D, G and H).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0034894.g005