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Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice

Fig 5

HFCD promotes inflammation in the pancreas of KC mice.

Inflammatory parameters in the histological sections of pancreas were evaluated quantitatively. Specifically, acinar loss scores, inflammatory scores, fibrosis scores, and pancreatitis indices were determined for male and female KC mice fed the CD or HFCD for different time periods. The values are means ± SD. *P<0.05, Student’s t-tests.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0184455.g005