Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes
Fig 5
Loss of epidermal Gαq correlates with defects in reepithelialization of cutaneous wounds.
Top panel: the epithelial tongue as evidenced by H&E staining (yellow dashed line) is diagrammed and the length quantified. Representative stains and quantification of Ki67 (second panel), K10 (third panel), and K13 (bottom panel) are shown. All quantifications are based on an N = 4 mice per group and proliferation is shown relative to normal adjacent epithelium. Slope was determined by linear regression and statistical significance was determined by Student’s t-test, p<0.05, **p<0.01, ***p<0.001.