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N-Acetyl-L-Leucine Accelerates Vestibular Compensation after Unilateral Labyrinthectomy by Action in the Cerebellum and Thalamus

Fig 5

Regional cerebral glucose metabolism after N-acetyl-D-leucine as compared to sham treatment following unilateral labyrinthectomy.

The images depict group-wise comparisons of the regional cerebral glucose metabolism (rCGM) on days 1, 3, 7 and 15 after unilateral labyrinthectomy (UL). The N-acetyl-D-leucine group (24 mg i.v. per rat) showed an increase of rCGM in the centromedian thalamus and hypothalamic area compared to the sham treatment group on day 7. There were no further differences of rCGM in any other cerebral region at any other time point. R right, L left, C caudal, Ro rostral, St subthalamic region, Th thalamus; p-value < 0.001

Fig 5

doi: https://doi.org/10.1371/journal.pone.0120891.g005