Concomitant Detection of HER2 Protein and Gene Alterations by Immunohistochemistry (IHC) and Silver Enhanced In Situ Hybridization (SISH) Identifies HER2 Positive Breast Cancer with and without Gene Amplification
Figure 5
Correlation of IHC score 2+ scores and amplification status by SISH to overall survival.
Amplification status in patients with IHC score 2+ had no impact on overall survival (Kaplan Meier curves).