Combined Strategy of Endothelial Cells Coating, Sertoli Cells Coculture and Infusion Improves Vascularization and Rejection Protection of Islet Graft
Figure 5
Improvement of SCs co-culture to the effect of ECs coating islets.
Immunofluorescence showed that nearly no vWF positive ECs were detected around islets in control group (islets only) after 7 days culture. ECs expressing vWF were still detectable in ECs coating and SCs coculture groups by 7 days culture. The islets in combined strategy group had the most vWF-positive ECs around it after 7 days co-culture. * P<0.05 vs. islet and SCs coculture, # P<0.05 vs. ECs coating, n = 10.