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CD4+CD25+Foxp3+ Regulatory T Cells Depletion May Attenuate the Development of Silica-Induced Lung Fibrosis in Mice

Figure 5

Treg cells affect the Th1/Th2 balance in the mice model of silica-induced lung fibrosis.

Typical Th1 (IL-2) (A) and Th2 (IL-4)(B) cytokines were assayed by realtime RT-PCR by using -△△Ct method. (n = 5) (*, as compare with the saline control group, P<0.05; △, as compare with the silica group, P<0.05; #, as compare with 7day of the same group, P<0.05).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0015404.g005