MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma
Figure 5
High-resolution molecular imaging of xenografted MB cells injected into the cerebellum.
PET-CT fusion images of AdV5-Mock#7 (A) and AdV5-199b#5 (B) mice at 12 weeks from surgery and injection, with 3D volume rendering and simultaneous display of areas of FLT uptake (blue–green, white arrows). A wider bone defect in the occipito-parietal portion of the skull is apparent in the AdV5-Mock#7 mouse. Below: table of measurements (cm3) of tumor mass undertaken with PET-CT acquisition (as described in Text S1).