Proteome expression profiling of red blood cells during the tumorigenesis of hepatocellular carcinoma
Fig 4
Alterations in RBCs at the onset of LC.
A. Hierarchical clustering analysis of LC and HC groups based on DEPs. A solid triangle indicates SMIM1 and ANXA7, respectively. B. Volcanic plot of DEPs from protein differential expression analysis in LC and HC groups (P < 0.05). SMIM1 and ANXA7 are highlighted with an arrow. C. Interactive networks that connect disrupted pathways and proteins in RBCs at the onset of LC. The networks were constructed using significant DEPs in LC and HC groups according to STRING analysis.