Action Mechanism of Fibroblast Growth Factor-2 (FGF-2) in the Promotion of Periodontal Regeneration in Beagle Dogs
Fig 4
Numbers of proliferating cells in the bone defect.
(A): Schematic of the measurement regions. The defect was compartmentalized into four zones: outside, margin, center, and upper. We evaluated 4 mm2 in the outside zone, 6 mm2 in the margin zone, 1 mm2 in the center zone, and 3 mm2 in the upper zone per defect. (B–E): Y-axis values represent the number of PCNA-positive cells per 1 mm2. All results are presented as the mean ± SD (n = 4) (*, p <0.05; **, p <0.01 compared with the control, t-test).