CD44-SNA1 integrated cytopathology for delineation of high grade dysplastic and neoplastic oral lesions
Fig 4
Delineating OSCC and HGD from Low Risk Lesions.
Graph depicting Receiver Operating Characteristic (ROC) curve Analysis of immunohistochemistry (A,B) and multiplex-Immunocytology (C,D) validation of markers. Combination of markers delineated HRL/HGD from LRL by immunohistochemistry (AUC: 0.96). CD44 and SNA-1 showed best AUC in histology (A) and cytology (C, D) in delineating HRL and HGD. AUC: Area Under Curve, HGD: High Grade Dysplasia, HRL: High Risk Lesion (OSCC+HGD), LRL: Low Risk Lesions.