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Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats

Fig 4

Erythropoietin treatment increases TMPRSS6 protein content in Bmp6-mutant mice.

(A) Increase of TMPRSS6 protein content in Bmp6-mutant mice mice treated with saline (C) or EPO (E) at 50 I.U./mouse for four days. Arrow denotes TMPRSS6-specific band. ATP1A is used as loading control. (B) TMPRSS6 band density quantification. (C and D) Effect of EPO treatment on Tmprss6 and Hamp mRNA content. Tmprss6 and Hamp mRNA content is determined relative to Actb mRNA.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0148540.g004