Interferon Beta and Vitamin D Synergize to Induce Immunoregulatory Receptors on Peripheral Blood Monocytes of Multiple Sclerosis Patients
Figure 4
CSF monocytes express high levels of ILT3.
(A) Paired blood and CSF samples were analyzed for expression of ILT3 on CD14+ monocytes by flow cytometry. The specific fluorescent index is shown. Patients were categorized according to their diagnosis as having non-inflammatory neurological diseases (NIND, n = 14; marked by dot) or inflammatory neurological disease (IND, n = 8) including 5 MS patients (marked by x) and 3 patients with other inflammatory neurological disease (diamond). A Mann-Whitney U test was performed to assess statistical significance. (B) Histogram of a representative staining in a patient with NIND.