Electronegative Low-Density Lipoprotein Increases C-Reactive Protein Expression in Vascular Endothelial Cells through the LOX-1 Receptor
Figure 4
Effects of lectin-like oxidized LDL receptor-1 (LOX-1) inhibition in human aortic endothelial cells (HAECs).
(A) HAECs were pretreated with LOX-1 neutralizing antibody TS92 before the introduction of L1 or L5 into cell culture. (B) HAECs were pretreated with TS92 before the introduction of recombinant human CRP (5 or 50 µg/mL) into cell culture. For all experiments, n = 3, and bars shown in graphs represent standard deviation. *P<0.05 vs. untreated control.