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DNA Methylation Changes in Atypical Adenomatous Hyperplasia, Adenocarcinoma In Situ, and Lung Adenocarcinoma

Figure 4

“Intermediate” DNA methylation changes: scatterplots of loci significantly hypermethylated in AIS lesions compared to AAH.

p-values were calculated by GEE, with a Bonferroni cutoff of p<0.017 (see Methods). Statistically significant differences are marked with an asterisk. Interquartile ranges are marked with red bars.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0021443.g004