A Comprehensive Microarray-Based DNA Methylation Study of 367 Hematological Neoplasms
Figure 4
Venn diagrams showing the overlap of genes.
(A) Hypermethylated or (B) hypomethylated in B-cell, T-cell and myeloid neoplasms. Only six genes were significantly hypermethylated in neoplasms of B-cell, T-cell and myeloid origin. We did not detect any gene hypomethylated in tumors of all three cellular origins. (C) Heatmap containing all the CpGs hypermethylated (above) or hypomethylated (below) in at least one HN subtype. CpGs are arranged in decreasing order of hypermethylation frequency. The presence of hypermethylated or hypomethylated CpGs in a given HN subtype is shown on the right of the heatmap (black: differentially methylated).