Inhibitory activity of pentacyano(isoniazid)ferrate(II), IQG-607, against promastigotes and amastigotes forms of Leishmania braziliensis
Fig 3
Cytotoxic activity of IQG-607 against cell lines.
HepG2 (A), Vero (B) e HaCat (C) cells were treated with IQG-607 for 72 h and cell viability was assessed by neutral red uptake assay. DNA damage index (D) were measured by alkaline comet assay in HepG2 cell after 24 h of IQG-607 (1 mM) or MMS (0.1 mM; positive control) exposure. Data is represented by mean±SD. One-way ANOVA followed by Bonferroni’s post-test were used in the statistical analyses, *P<0.05, **P<0.01 and ***P<0.001.