Computational and biological evidences on the serotonergic involvement of SeTACN antidepressant-like effect in mice
Fig 3
Docking results of compound 4 (5-(4methoxyphenyl)-1-(2- (phenylselanyl)phenyl)-1H-1,2,3-triazole-4-carbonitrile (SeTACN) in (A) serotonin transporter (SERT) with a score of -9.9kcal/mol (B) in 5HT1a receptor with a score of -8.8kcal/mol (C) in 5HT2a receptor with a score of -8.8kcal/mol (D) and in 5HT3 receptor with a score of -8.1kcal/mol.