Epigenome-Wide DNA Methylation in Hearing Ability: New Mechanisms for an Old Problem
Figure 3
DNA methylation association with hearing PC1 at TCF25 and POLE
. Hearing PC1 association with all available Illumina 450 k DNA methylation probes annotated to TCF25 (A) and POLE (B) gene regions according to hg19. Significance of association with hearing PC1 expressed as the negative logarithm of the p-value was plotted against base pair [bp] location for chromosomes 16 and 12, respectively. The red horizontal lines represent the significance threshold for nominal significance (p = 0.05).