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Puerarin blocks the aging phenotype in human dermal fibroblasts

Fig 3

The effect of puerarin on cellular senescence in high-passage NHDFs.

A, B: The effect of puerarin on SA-β-galactosidase activity. Young and senescent (sene) NHDFs treated with 20 or 50 μM puerarin (pue) were stained by SA-β-galactosidase assay (A). The percentage of SA-β-galactosidase positive cells per total cells was calculated from 15 microscopic fields for each group. Scale bars = 100 μm.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0249367.g003