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Mucolytic Effectiveness of Tyloxapol in Chronic Obstructive Pulmonary Disease - A Double-Blind, Randomized Controlled Trial

Fig 3

Sputum weight before processing comparing Tyloxapol and saline.

The figures illustrate (A-C) the sputum weight of patients treated with Tyloxapol and saline before further processing at (A) day 1 (n = 19 vs. 18), (B) 1 week (n = 19 vs. 17) and (C) 3 weeks of inhalation (n = 18 vs. 16), and (D) the fitted mixed linear model for the weight of sputum secretion [g]. The black lines represent the predicted mean of each therapy arm. The grey lines represent the observed values by each test person at day 1, 7 and 21. *, p < 0.05; *** p < 0.001; p-values were calculated using the Mann-Whitney test.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0156999.g003